Category pftblog

What’s abnormal about FRC?

I’ve had a number of reports across my desk in the last couple of weeks with both elevated and reduced FRC’s that were associated with a more-or-less normal TLC. I reviewed the raw data…

DMCO, Vc and 1/theta

Roughton and Forester’s seminal paper from the 1950’s showed that DLCO was a function of two resistances: the alveolar-capillary membrane and the rate of CO uptake by red blood cells. T…

DLO2/Qc, SaO2 and CPETs

There are a number of simple observations that can be made during a cardio-pulmonary exercise test (CPET) that can point you immediately in a specific diagnostic direction. Recently I was reminded …